Men - androgenic deficit after castrating, eunuchoidism, impotence hormonal origin, symptoms of male climax (decreased libido and physical and intellectual activity) in acromegaly, in early-stage prostate hypertrophy, osteoporosis caused by androgenic insufficiency; forms Angioneurotic angina pectoris.
Women - vascular and nerve disorders climacteric, when preparations against estrogen (ovarian and breast cancer, uterine bleeding) concomitantly with radiotherapy in breast and ovarian cancer (usually in women aged under 60 years) in dysfunctional uterine bleeding women over 45 years.
Persons that have hypersensitivity towards the medication, with the prostate related or perhaps cancer of the breast, prostatic hypertrophy with symptoms of urinary system problems, nephrotic syndrome or even the nephrotic period associated with nephritis, edema, hypercalcemia, hepatic dysfunction, diabetes mellitus, and coronary heart disease, myocardial infarction with inside anamnesis, atherosclerosis in older males, being pregnant, breast-feeding.
Intramuscular injection, heavy with inside the gluteal muscle. Dosing routine is actually altered separately, with regards to the disease, intercourse, grow older, clinical result.
The most frequent serving agenda for this kind of ingredient (men) is to provide 50 mg in order to be able for you to help 100mg, every single day or even 2nd evening. Much like the greater well-known esters, the whole each week dosage will be inside range of 300-700mg.
Gastric lavage, compelled alkalic symptom, restoration associated with liquid, solution and chemical stability, dialysis and also supportive remedy are usually necessary
Testosterone is the main androgen hormone combined and also released by the testicles. It is in charge of progression of men sexual intercourse organs and also extra sex qualities (readiness regarding prostate related, seminal vesicles, penis as well as scrotum), man head of curly tresses distribution (encounter, pubic bone, upper body) building laryngeal muscle tissue and the body extra weight syndication. Contain the N, sodium, blood potassium and phosphorus, increases protein constructive metabolism and reduce catabolism. Rapid improve plasma concentrations regarding androgen hormone or the male growth hormone in prepubertal causes stunted progress as well as epiphyseal closure. Induces manufacture of glycoprotein and also erythrocytes. With the suggestions device inhibits pituitary LH and hair follicle and causes reductions associated with spermatogenesis.
In case of adverse reactions androgen-dependent, stop taking preparation. After the disappearance of side effects, repeated the treatment in smaller doses.
Patients with latent or overt cardiac, impaired renal function, hypertension, epilepsy or migraine (or a history of the presence of these conditions) will be under constant supervision because androgens may cause the sodium and water retention. The treatment duration will monitoring liver functions. In patients with breast cancer, hypernephroma, lung cancer bone metastases will control the level of calcium in blood and urine. Androgens in prepubertal adolescents should be given with caution to avoid premature cessation of growth and puberty.
- Priapism and other symptoms of sexual hyper stimulation (frequent erection);
- Prepubertal age teenagers - accelerate sexual development, increased frequency of erections, increased sexual organ size, premature closure of the epiphyseal
- impaired spermatogenesis and sperm maturation disorder, oligospermia and reduced volume of ejaculate;
- Abnormalities of the prostate;
- Women - bleeding from the genital tracts, increased libido, prolonged administration of virilization symptoms are possible;
- Hirsutism, gynecomastia;
- Seborrhea, acne, oily skin, hair lose;
- Sodium and water retention, edema;
- Symptoms of hypercalcemia;
- Thrombophlebitis;
- Nausea, cholestatic jaundice, increased liver transaminase levels (normalized to discontinuation);
- Headache, depression, aggression, anxiety, sleep disorders, numbness.
Possible pain, itching and redness at the injection site.
With inside acute over dosage associated with testosterone accumulation is fairly low.
Throughout persistent drug can be done to develop pathology. In this case it is necessary to prevent using preparing, and also right immediately soon just once disappearance of symptoms - the actual started again remedy from lower dosages.
Gastric lavage, compelled alkalic symptom, restoration associated with liquid, solution and chemical stability, dialysis and also supportive remedy are usually necessary